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Archived Comments for: A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient

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  1. New algorithm to compute the flux spectrum

    Francisco Llaneras, Technical University of Valencia

    5 February 2008

    We have described a modified algorithm to compute the flux spectrum that overcomes a limitation of the one given in this paper. The old algorithm (eq. 10) can lead to a slight, but unnecessary, magnification of the effect of the uncertainty. We have checked that this effect is negligible in the examples used to illustrate the paper; However, the new algorithm will yield slightly better results in the general case.

    You can find details about the new algorithm, the new matlab files and other resources concerning this work in the following webpage: http://science.ensilicio.com/

    (section "flux spectrum approach")

    Please contact us with any doubt, to discuss the paper or to suggest any kind of collaboration.

    Best regards,

    the authors

    --

    Francisco Llaneras

    Dept. of Systems Engineering and Control

    Technical University of Valencia

    frallaes@doctor.upv.es | http://science.ensilicio.com/

    Competing interests

    I am one of the authors of the paper.

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