Open Access

Erratum to: How can functional annotations be derived from profiles of phenotypic annotations?

  • Beatriz Serrano-Solano1,
  • Antonio Díaz Ramos2,
  • Jean-Karim Hériché3 and
  • Juan A. G. Ranea1, 4Email author
BMC BioinformaticsBMC series – open, inclusive and trusted201718:194

DOI: 10.1186/s12859-017-1607-y

Received: 15 March 2017

Accepted: 15 March 2017

Published: 27 March 2017

The original article was published in BMC Bioinformatics 2017 18:96

Erratum

Upon publication of this article [1], it was brought to our attention that Table 1 was incorrectly presented. The correct Table 1 is shown below and has been updated in the original article.
Table 1

Set of 36 phenotypes obtained from the listed siRNA experiments sorted by its CMPO identifier

Experiment

Description

Phenotypes

IDs in CMPO

CellMorph [3]

Genome-wide RNAi screen that examines changes in the morphology of individual HeLa cells within cell populations.

- Decreased cell number

- Cell with projections

- Elongated cell

- More lamellipodia cells

- Increased number of actin filament

- Round cell

- Increased cell size

- Decreased cell size

- Bright nuclei

- Metaphase arrested

- Increased cell size in population

CMPO:0000052

CMPO:0000071

CMPO:0000077

CMPO:0000083

CMPO:0000105

CMPO:0000118

CMPO:0000128

CMPO:0000129

CMPO:0000154

CMPO:0000305

CMPO:0000340

MitoCheck [2]

Genome-wide RNAi screen for genes required for chromosome segregation in HeLa cells. The screen also reports genes involved in other processes such as cell movement.

- Cell death

- Increased nucleus size

- Graped micronucleus

- Abnormal nucleus shape

- Mitosis delayed

- Binuclear cell

- Absence of mitotic chromosome decondensation

- Increased cell movement speed

- Increased cell movement distance

- Proliferating cells

- Metaphase delayed

- Abnormal chromosome segregation

- Prometaphase delayed

- Increased variability of nuclear shape in population

- Mitotic metaphase plate congression

CMPO:0000030

CMPO:0000140

CMPO:0000156

CMPO:0000157

CMPO:0000202

CMPO:0000213

CMPO:0000216

CMPO:0000236

CMPO:0000237

CMPO:0000241

CMPO:0000307

CMPO:0000326

CMPO:0000344

CMPO:0000345

CMPO:0000348

EMBL secretion [4]

Genome-wide RNAi screen for interference with ER-to-plasma membrane transport of the secretory cargo protein tsO45G in HeLa cells.

- Increased rate of protein secretion

- Mild decrease in rate of protein secretion

- Strong decrease in rate of protein secretion

- Decreased rate of intracellular protein transport

CMPO:0000246

CMPO:0000318

CMPO:0000319

CMPO:0000346

GR00053 [10]

Genome-wide RNAi screen for genes involved in DNA damage responses in HeLa cells.

- Increased number of site of double-strand break

CMPO:0000182

GR00290 [9]

Genome-wide RNAi screen for genes regulating centriole formation in HeLa cells.

- Increased centriole replication

- Decreased centriole replication

CMPO:0000361

CMPO:0000362

Copenhagen DNA damage Ubiquitin [8]

RNAi screen of >1300 genes involved in the ubiquitin-proteasome system or encoding zinc-finger proteins looking for modulators of cellular responses to ionizing radiation in HeLa and U2OS cells.

- Decreased number of site of double-strand brea

CMPO:0000181

EMBL chromosome condensation [7]

RNAi screen of 100 bioinformatically-selected genes for changes in mitotic prophase duration in HeLa cells.

- Increased duration of mitotic prophase

- Decreased duration of mitotic prophase

CMPO:0000328

CMPO:0000329

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Department of Molecular Biology and Biochemistry, University of Málaga
(2)
Department of Algebra, Geometry and Topology, University of Málaga
(3)
European Molecular Biology Laboratory
(4)
CIBER de Enfermedades raras (CIBERER)

Reference

  1. Serrano-Solano B, et al. How can functional annotations be derived from profiles of phenotypic annotations? BMC Bioinformatics. 2017;18:96. doi:10.1186/s12859-017-1503-5.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s). 2017

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