Open Access

Erratum to: Guide Picker is a comprehensive design tool for visualizing and selecting guides for CRISPR experiments

  • Soren H. Hough1Email author,
  • Kris Kancleris1,
  • Leigh Brody1,
  • Neil Humphryes-Kirilov1,
  • Joseph Wolanski1,
  • Keith Dunaway1,
  • Ayokunmi Ajetunmobi1 and
  • Victor Dillard1
Contributed equally
BMC BioinformaticsBMC series – open, inclusive and trusted201718:202

DOI: 10.1186/s12859-017-1618-8

Received: 28 March 2017

Accepted: 29 March 2017

Published: 4 April 2017

The original article was published in BMC Bioinformatics 2017 18:167

Erratum

Following publication of this article [1], it has come to our attention that a caption for figure 6 is incorrect. Presently, it reads “Fig. 6 Designing a Tiling Experiment with Guide Picker. a First, guides are plotted along the length of the MCDS using percent peptide on the x-axis. The y-axis is set to Doench 2016 Positionless. b Filtering guides to a strict score threshold (e.g. < 55) offers a panel of guides that still target along the full length of the MCDS. c The right-hand plot can then be set and filtered according to other guide parameters, such as GC (30–70%) content and Hsu 2013 ( < 68) off-target scoring. d The guides in this range can then be highlighted to verify that this select group of guides still target along the full length of the MCDS in the left-hand plot”. However, the less than (<) symbols should be more than (>) symbols and the caption should read, “Fig. 6 Designing a Tiling Experiment with Guide Picker. a First, guides are plotted along the length of the MCDS using percent peptide on the x-axis. The y-axis is set to Doench 2016 Positionless. b Filtering guides to a strict score threshold (e.g. >55 ) offers a panel of guides that still target along the full length of the MCDS. c The right-hand plot can then be set and filtered according to other guide parameters, such as GC (30–70%) content and Hsu 2013 ( >68 ) off-target scoring. d The guides in this range can then be highlighted to verify that this select group of guides still target along the full length of the MCDS in the left-hand plot.”

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)

Reference

  1. Hough S, Kancleris K, Brody L, Humphryes-Kirilov N, Wolanski J, Dunaway K, Ajetunmobi A, Dillard V. Guide Picker is a comprehensive design tool for visualizing and selecting guides for CRISPR experiments. BMC Bioinformatics. 2017;18:167. doi:10.1186/s12859-017-1581-4.View ArticlePubMedPubMed CentralGoogle Scholar

Copyright

© The Author(s). 2017

Advertisement