Volume 13 Supplement 14

Research from the Eleventh International Workshop on Network Tools and Applications in Biology (NETTAB 2011)

Research

Edited by Riccardo Bellazzi, Paolo Romano, Marco Masseroli, Shawn Murphy and Amnon Shabo

NETTAB 2011 Workshop on Clinical Bioinformatics. Go to conference site.

Pavia, Italy

12-14 October 2011

  1. Introduction

    Clinical Bioinformatics: challenges and opportunities

    Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop,...

    Riccardo Bellazzi, Marco Masseroli, Shawn Murphy, Amnon Shabo and Paolo Romano

    BMC Bioinformatics 2012 13(Suppl 14):S1

    Published on: 7 September 2012

  2. Research

    Bag of Naïve Bayes: biomarker selection and classification from genome-wide SNP data

    Multifactorial diseases arise from complex patterns of interaction between a set of genetic traits and the environment. To fully capture the genetic biomarkers that jointly explain the heritability component o...

    Francesco Sambo, Emanuele Trifoglio, Barbara Di Camillo, Gianna M Toffolo and Claudio Cobelli

    BMC Bioinformatics 2012 13(Suppl 14):S2

    Published on: 7 September 2012

  3. Research

    Cancer module genes ranking using kernelized score functions

    Co-expression based Cancer Modules (CMs) are sets of genes that act in concert to carry out specific functions in different cancer types, and are constructed by exploiting gene expression profiles related to s...

    Matteo Re and Giorgio Valentini

    BMC Bioinformatics 2012 13(Suppl 14):S3

    Published on: 7 September 2012

  4. Research

    Hierarchical Naive Bayes for genetic association studies

    Genome Wide Association Studies represent powerful approaches that aim at disentangling the genetic and molecular mechanisms underlying complex traits. The usual "one-SNP-at-the-time" testing strategy cannot c...

    Alberto Malovini, Nicola Barbarini, Riccardo Bellazzi and Francesca De Michelis

    BMC Bioinformatics 2012 13(Suppl 14):S6

    Published on: 7 September 2012

  5. Research

    Imputation reliability on DNA biallelic markers for drug metabolism studies

    Imputation is a statistical process used to predict genotypes of loci not directly assayed in a sample of individuals. Our goal is to measure the performance of imputation in predicting the genotype of the bes...

    Vladan Mijatovic, Ilaria Iacobucci, Marco Sazzini, Luciano Xumerle, Antonio Mori, Pier Franco Pignatti, Giovanni Martinelli and Giovanni Malerba

    BMC Bioinformatics 2012 13(Suppl 14):S7

    Published on: 7 September 2012

  6. Research

    GapFiller: a de novo assembly approach to fill the gap within paired reads

    Next Generation Sequencing technologies are able to provide high genome coverages at a relatively low cost. However, due to limited reads' length (from 30 bp up to 200 bp), specific bioinformatics problems hav...

    Francesca Nadalin, Francesco Vezzi and Alberto Policriti

    BMC Bioinformatics 2012 13(Suppl 14):S8

    Published on: 7 September 2012

  7. Research

    EVA: Exome Variation Analyzer, an efficient and versatile tool for filtering strategies in medical genomics

    Whole exome sequencing (WES) has become the strategy of choice to identify a coding allelic variant for a rare human monogenic disorder. This approach is a revolution in medical genetics history, impacting bot...

    Sophie Coutant, Chloé Cabot, Arnaud Lefebvre, Martine Léonard, Elise Prieur-Gaston, Dominique Campion, Thierry Lecroq and Hélène Dauchel

    BMC Bioinformatics 2012 13(Suppl 14):S9

    Published on: 7 September 2012

  8. Research

    The human "magnesome": detecting magnesium binding sites on human proteins

    Magnesium research is increasing in molecular medicine due to the relevance of this ion in several important biological processes and associated molecular pathogeneses. It is still difficult to predict from th...

    Damiano Piovesan, Giuseppe Profiti, Pier Luigi Martelli and Rita Casadio

    BMC Bioinformatics 2012 13(Suppl 14):S10

    Published on: 7 September 2012

  9. Research

    Matching health information seekers' queries to medical terms

    The Internet is a major source of health information but most seekers are not familiar with medical vocabularies. Hence, their searches fail due to bad query formulation. Several methods have been proposed to ...

    Lina F Soualmia, Elise Prieur-Gaston, Zied Moalla, Thierry Lecroq and Stéfan J Darmoni

    BMC Bioinformatics 2012 13(Suppl 14):S11

    Published on: 7 September 2012

  10. Research

    Modelling osteomyelitis

    This work focuses on the computational modelling of osteomyelitis, a bone pathology caused by bacteria infection (mostly Staphylococcus aureus). The infection alters the RANK/RANKL/OPG signalling dynamics that re...

    Pietro Liò, Nicola Paoletti, Mohammad Ali Moni, Kathryn Atwell, Emanuela Merelli and Marco Viceconti

    BMC Bioinformatics 2012 13(Suppl 14):S12

    Published on: 7 September 2012

  11. Research

    High-Throughput parallel blind Virtual Screening using BINDSURF

    Virtual Screening (VS) methods can considerably aid clinical research, predicting how ligands interact with drug targets. Most VS methods suppose a unique binding site for the target, usually derived from the ...

    Irene Sánchez-Linares, Horacio Pérez-Sánchez, José M Cecilia and José M García

    BMC Bioinformatics 2012 13(Suppl 14):S13

    Published on: 7 September 2012