Volume 13 Supplement 14
Research from the Eleventh International Workshop on Network Tools and Applications in Biology (NETTAB 2011)
Research
Edited by Riccardo Bellazzi, Paolo Romano, Marco Masseroli, Shawn Murphy and Amnon Shabo
NETTAB 2011 Workshop on Clinical Bioinformatics. Go to
conference site.
Pavia, Italy
12-14 October 2011
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Introduction
Network Tools and Applications in Biology (NETTAB) Workshops are a series of meetings focused on the most promising and innovative ICT tools and to their usefulness in Bioinformatics. The NETTAB 2011 workshop,...
Riccardo Bellazzi, Marco Masseroli, Shawn Murphy, Amnon Shabo and Paolo Romano
BMC Bioinformatics 2012 13(Suppl 14):S1
Published on: 7 September 2012
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Research
Multifactorial diseases arise from complex patterns of interaction between a set of genetic traits and the environment. To fully capture the genetic biomarkers that jointly explain the heritability component o...
Francesco Sambo, Emanuele Trifoglio, Barbara Di Camillo, Gianna M Toffolo and Claudio Cobelli
BMC Bioinformatics 2012 13(Suppl 14):S2
Published on: 7 September 2012
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Research
Co-expression based Cancer Modules (CMs) are sets of genes that act in concert to carry out specific functions in different cancer types, and are constructed by exploiting gene expression profiles related to s...
Matteo Re and Giorgio Valentini
BMC Bioinformatics 2012 13(Suppl 14):S3
Published on: 7 September 2012
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Research
Hospitals nowadays have to serve numerous patients with limited medical staff and equipment while maintaining healthcare quality. Clinical pathway informatics is regarded as an efficient way to solve a series ...
Xian Yang, Rui Han, Yike Guo, Jeremy Bradley, Benita Cox, Robert Dickinson and Richard Kitney
BMC Bioinformatics 2012 13(Suppl 14):S4
Published on: 7 September 2012
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Research
Inflammatory bowel diseases (IBD) refer to a group of inflammatory conditions concerning colon and small intestine, which cause socially uncomfortable symptoms and often are associated with an increased risk o...
I Merelli, F Viti and L Milanesi
BMC Bioinformatics 2012 13(Suppl 14):S5
Published on: 7 September 2012
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Research
Genome Wide Association Studies represent powerful approaches that aim at disentangling the genetic and molecular mechanisms underlying complex traits. The usual "one-SNP-at-the-time" testing strategy cannot c...
Alberto Malovini, Nicola Barbarini, Riccardo Bellazzi and Francesca De Michelis
BMC Bioinformatics 2012 13(Suppl 14):S6
Published on: 7 September 2012
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Research
Imputation is a statistical process used to predict genotypes of loci not directly assayed in a sample of individuals. Our goal is to measure the performance of imputation in predicting the genotype of the bes...
Vladan Mijatovic, Ilaria Iacobucci, Marco Sazzini, Luciano Xumerle, Antonio Mori, Pier Franco Pignatti, Giovanni Martinelli and Giovanni Malerba
BMC Bioinformatics 2012 13(Suppl 14):S7
Published on: 7 September 2012
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Research
Next Generation Sequencing technologies are able to provide high genome coverages at a relatively low cost. However, due to limited reads' length (from 30 bp up to 200 bp), specific bioinformatics problems hav...
Francesca Nadalin, Francesco Vezzi and Alberto Policriti
BMC Bioinformatics 2012 13(Suppl 14):S8
Published on: 7 September 2012
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Research
Whole exome sequencing (WES) has become the strategy of choice to identify a coding allelic variant for a rare human monogenic disorder. This approach is a revolution in medical genetics history, impacting bot...
Sophie Coutant, Chloé Cabot, Arnaud Lefebvre, Martine Léonard, Elise Prieur-Gaston, Dominique Campion, Thierry Lecroq and Hélène Dauchel
BMC Bioinformatics 2012 13(Suppl 14):S9
Published on: 7 September 2012
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Research
Magnesium research is increasing in molecular medicine due to the relevance of this ion in several important biological processes and associated molecular pathogeneses. It is still difficult to predict from th...
Damiano Piovesan, Giuseppe Profiti, Pier Luigi Martelli and Rita Casadio
BMC Bioinformatics 2012 13(Suppl 14):S10
Published on: 7 September 2012
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Research
The Internet is a major source of health information but most seekers are not familiar with medical vocabularies. Hence, their searches fail due to bad query formulation. Several methods have been proposed to ...
Lina F Soualmia, Elise Prieur-Gaston, Zied Moalla, Thierry Lecroq and Stéfan J Darmoni
BMC Bioinformatics 2012 13(Suppl 14):S11
Published on: 7 September 2012
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Research
This work focuses on the computational modelling of osteomyelitis, a bone pathology caused by bacteria infection (mostly Staphylococcus aureus). The infection alters the RANK/RANKL/OPG signalling dynamics that re...
Pietro Liò, Nicola Paoletti, Mohammad Ali Moni, Kathryn Atwell, Emanuela Merelli and Marco Viceconti
BMC Bioinformatics 2012 13(Suppl 14):S12
Published on: 7 September 2012
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Research
Virtual Screening (VS) methods can considerably aid clinical research, predicting how ligands interact with drug targets. Most VS methods suppose a unique binding site for the target, usually derived from the ...
Irene Sánchez-Linares, Horacio Pérez-Sánchez, José M Cecilia and José M García
BMC Bioinformatics 2012 13(Suppl 14):S13
Published on: 7 September 2012
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Research
Reaction-diffusion based models have been widely used in the literature for modeling the growth of solid tumors. Many of the current models treat both diffusion/consumption of nutrients and cell proliferation....
Paola Lecca and Daniele Morpurgo
BMC Bioinformatics 2012 13(Suppl 14):S14
Published on: 7 September 2012