Volume 14 Supplement 16

Twelfth International Conference on Bioinformatics (InCoB2013): Bioinformatics

Proceedings

Edited by Shoba Ranganathan, Christian Schönbach, Tin Wee Tan and Bairong Shen

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Asia Pacific Bioinformatics Network (APBioNet) Twelfth International Conference on Bioinformatics (InCoB2013). Go to conference site.

Taicang, China

20-22 September 2013

  1. Research

    Incorporating substrate sequence motifs and spatial amino acid composition to identify kinase-specific phosphorylation sites on protein three-dimensional structures

    Protein phosphorylation catalyzed by kinases plays crucial regulatory roles in cellular processes. Given the high-throughput mass spectrometry-based experiments, the desire to annotate the catalytic kinases for i...

    Min-Gang Su and Tzong-Yi Lee

    BMC Bioinformatics 2013 14(Suppl 16):S2

    Published on: 22 October 2013

  2. Research

    Pathway-based drug repositioning using causal inference

    Recent in vivo studies showed new hopes of drug repositioning through causality inference from drugs to disease. Inspired by their success, here we present an in silico method for building a causal network (Cause...

    Jiao Li and Zhiyong Lu

    BMC Bioinformatics 2013 14(Suppl 16):S3

    Published on: 22 October 2013

  3. Research

    Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the presence of mutation R289K

    Since late March 2013, there has been another global health concern with a sudden wave of flu infections by a novel strain of avian influenza A (H7N9) virus in China. To-date, there have been more than 100 inf...

    Chinh Tran-To Su, Xuchang Ouyang, Jie Zheng and Chee-Keong Kwoh

    BMC Bioinformatics 2013 14(Suppl 16):S7

    Published on: 22 October 2013

  4. Research

    Structural analysis on mutation residues and interfacial water molecules for human TIM disease understanding

    Human triosephosphate isomerase (HsTIM) deficiency is a genetic disease caused often by the pathogenic mutation E104D. This mutation, located at the side of an abnormally large cluster of water in the inter-su...

    Zhenhua Li, Ying He, Qian Liu, Liang Zhao, Limsoon Wong, Chee Keong Kwoh, Hung Nguyen and Jinyan Li

    BMC Bioinformatics 2013 14(Suppl 16):S11

    Published on: 22 October 2013

  5. Research

    HCS-Neurons: identifying phenotypic changes in multi-neuron images upon drug treatments of high-content screening

    High-content screening (HCS) has become a powerful tool for drug discovery. However, the discovery of drugs targeting neurons is still hampered by the inability to accurately identify and quantify the phenotyp...

    Phasit Charoenkwan, Eric Hwang, Robert W Cutler, Hua-Chin Lee, Li-Wei Ko, Hui-Ling Huang and Shinn-Ying Ho

    BMC Bioinformatics 2013 14(Suppl 16):S12

    Published on: 22 October 2013

  6. Research

    MetaSel: a metaphase selection tool using a Gaussian-based classification technique

    Identification of good metaphase spreads is an important step in chromosome analysis for identifying individuals with genetic disorders. The process of finding suitable metaphase chromosomes for accurate clini...

    Ravi Uttamatanin, Peerapol Yuvapoositanon, Apichart Intarapanich, Saowaluck Kaewkamnerd, Ratsapan Phuksaritanon, Anunchai Assawamakin and Sissades Tongsima

    BMC Bioinformatics 2013 14(Suppl 16):S13

    Published on: 22 October 2013

  7. Research

    RMaNI: Regulatory Module Network Inference framework

    Cell survival and development are orchestrated by complex interlocking programs of gene activation and repression. Understanding how this gene regulatory network (GRN) functions in normal states, and is altered i...

    Piyush B Madhamshettiwar, Stefan R Maetschke, Melissa J Davis and Mark A Ragan

    BMC Bioinformatics 2013 14(Suppl 16):S14

    Published on: 22 October 2013