Volume 15 Supplement 1
Integrated Bio-Search: Selected Works from the 12th International Workshop on Network Tools and Applications in Biology (NETTAB 2012)
Research
Edited by Paolo Romano and Marco Masseroli
Integrated Bio-Search: 12th International Workshop on Network Tools and Applications in Biology (NETTAB 2012). Go to
conference site.
Como, Italy
14-16 November 2012
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Introduction
The NETTAB 2012 workshop, held in Como on November 14-16, 2012, was devoted to "Integrated Bio-Search", that is to technologies, methods, architectures, systems and applications for searching, retrieving, inte...
Paolo Romano, Frédérique Lisacek and Marco Masseroli
BMC Bioinformatics 2014 15(Suppl 1):S1
Published on: 10 January 2014
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Review
Many efforts exist to design and implement approaches and tools for data capture, integration and analysis in the life sciences. Challenges are not only the heterogeneity, size and distribution of information ...
Marco Masseroli, Barend Mons, Erik Bongcam-Rudloff, Stefano Ceri, Alexander Kel, François Rechenmann, Frederique Lisacek and Paolo Romano
BMC Bioinformatics 2014 15(Suppl 1):S2
Published on: 10 January 2014
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Research
The huge amount of biomedical-molecular data increasingly produced is providing scientists with potentially valuable information. Yet, such data quantity makes difficult to find and extract those data that are...
Marco Masseroli, Matteo Picozzi, Giorgio Ghisalberti and Stefano Ceri
BMC Bioinformatics 2014 15(Suppl 1):S3
Published on: 10 January 2014
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Research
MicroRNAs (miRNAs) are small non-coding RNAs which play a key role in the post-transcriptional regulation of many genes. Elucidating miRNA-regulated gene networks is crucial for the understanding of mechanisms...
Gianvito Pio, Donato Malerba, Domenica D'Elia and Michelangelo Ceci
BMC Bioinformatics 2014 15(Suppl 1):S4
Published on: 10 January 2014
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Research
Prioritization methods have become an useful tool for mining large amounts of data to suggest promising hypotheses in early research stages. Particularly, network-based prioritization tools use a network repre...
Víctor Martínez, Carlos Cano and Armando Blanco
BMC Bioinformatics 2014 15(Suppl 1):S5
Published on: 10 January 2014
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Software
The amount of gene expression data available in public repositories has grown exponentially in the last years, now requiring new data mining tools to transform them in information easily accessible to biologists.
Paolo Cremaschi, Sergio Rovida, Lucia Sacchi, Antonella Lisa, Francesca Calvi, Alessandra Montecucco, Giuseppe Biamonti, Silvia Bione and Gianni Sacchi
BMC Bioinformatics 2014 15(Suppl 1):S6
Published on: 10 January 2014
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Research
In the last decade, Next-Generation Sequencing technologies have been extensively applied to quantitative transcriptomics, making RNA sequencing a valuable alternative to microarrays for measuring and comparin...
Francesca Finotello, Enrico Lavezzo, Luca Bianco, Luisa Barzon, Paolo Mazzon, Paolo Fontana, Stefano Toppo and Barbara Di Camillo
BMC Bioinformatics 2014 15(Suppl 1):S7
Published on: 10 January 2014
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Software
Modern genomic technologies produce large amounts of data that can be mapped to specific regions in the genome. Among the first steps in interpreting the results is annotation of genomic regions with known fea...
Luca Zammataro, Rita DeMolfetta, Gabriele Bucci, Arnaud Ceol and Heiko Muller
BMC Bioinformatics 2014 15(Suppl 1):S8
Published on: 10 January 2014
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Research
Recent progress in method development for characterising the branched structures of complex carbohydrates has now enabled higher throughput technology. Automation of structure analysis then calls for software ...
Matthew P Campbell, René Ranzinger, Thomas Lütteke, Julien Mariethoz, Catherine A Hayes, Jingyu Zhang, Yukie Akune, Kiyoko F Aoki-Kinoshita, David Damerell, Giorgio Carta, Will S York, Stuart M Haslam, Hisashi Narimatsu, Pauline M Rudd, Niclas G Karlsson, Nicolle H Packer…
BMC Bioinformatics 2014 15(Suppl 1):S9
Published on: 10 January 2014
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Research
Single Nucleotide Polymorphism (SNP) genotyping analysis is very susceptible to SNPs chromosomal position errors. As it is known, SNPs mapping data are provided along the SNP arrays without any necessary infor...
Andrea Manconi, Alessandro Orro, Emanuele Manca, Giuliano Armano and Luciano Milanesi
BMC Bioinformatics 2014 15(Suppl 1):S10
Published on: 10 January 2014
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Research
The ISA-Tab format and software suite have been developed to break the silo effect induced by technology-specific formats for a variety of data types and to better support experimental metadata tracking. Exper...
Alejandra González-Beltrán, Steffen Neumann, Eamonn Maguire, Susanna-Assunta Sansone and Philippe Rocca-Serra
BMC Bioinformatics 2014 15(Suppl 1):S11
Published on: 10 January 2014
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Research
Scientific workflows management systems are increasingly used to specify and manage bioinformatics experiments. Their programming model appeals to bioinformaticians, who can use them to easily specify complex ...
Sarah Cohen-Boulakia, Jiuqiang Chen, Paolo Missier, Carole Goble, Alan R Williams and Christine Froidevaux
BMC Bioinformatics 2014 15(Suppl 1):S12
Published on: 10 January 2014
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Software
In recent years, the experimental aspects of the laboratory activities have been growing in complexity in terms of amount and diversity of data produced, equipment used, of computer-based workflows needed to p...
Piergiorgio Palla, Gianfranco Frau, Laura Vargiu and Patricia Rodriguez-Tomé
BMC Bioinformatics 2014 15(Suppl 1):S13
Published on: 10 January 2014
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Research
In the last decades, a wide number of researchers/clinicians involved in tissue engineering field published several works about the possibility to induce a tissue regeneration guided by the use of biomaterials...
Federica Viti, Silvia Scaglione, Alessandro Orro and Luciano Milanesi
BMC Bioinformatics 2014 15(Suppl 1):S14
Published on: 10 January 2014
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Research
The large increase in the size of patent collections has led to the need of efficient search strategies. But the development of advanced text-mining applications dedicated to patents of the biomedical field re...
Emilie Pasche, Julien Gobeill, Olivier Kreim, Fatma Oezdemir-Zaech, Therese Vachon, Christian Lovis and Patrick Ruch
BMC Bioinformatics 2014 15(Suppl 1):S15
Published on: 10 January 2014