Volume 15 Supplement 7

Selected articles from the 10th Annual Biotechnology and Bioinformatics Symposium (BIOT 2013)


Edited by Perry Ridge, Quinn Snell and Mark Clement

This supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard review process for supplements. The Supplement Editors declare that they have no competing interests.

The 10th Annual Biotechnology and Bioinformatics Symposium (BIOT 2013). Go to conference site.

Provo, UT, USA

5-6 December 2013

  1. Research

    Analysis of interactions between the epigenome and structural mutability of the genome using Genboree workbench tools

    Interactions between the epigenome and structural genomic variation are potentially bi-directional. In one direction, structural variants may cause epigenomic changes in cis. In the other direction, specific loca...

    Cristian Coarfa, Christina Stewart Pichot, Andrew Jackson, Arpit Tandon, Viren Amin, Sriram Raghuraman, Sameer Paithankar, Adrian V Lee, Sean E McGuire and Aleksandar Milosavljevic

    BMC Bioinformatics 2014 15(Suppl 7):S2

    Published on: 28 May 2014

  2. Research

    Effects of error-correction of heterozygous next-generation sequencing data

    Error correction is an important step in increasing the quality of next-generation sequencing data for downstream analysis and use. Polymorphic datasets are a challenge for many bioinformatic software packages...

    M Stanley Fujimoto, Paul M Bodily, Nozomu Okuda, Mark J Clement and Quinn Snell

    BMC Bioinformatics 2014 15(Suppl 7):S3

    Published on: 28 May 2014

  3. Research

    Identifying microRNA targets in different gene regions

    Currently available microRNA (miRNA) target prediction algorithms require the presence of a conserved seed match to the 5' end of the miRNA and limit the target sites to the 3' untranslated regions of mRNAs. H...

    Wenlong Xu, Anthony San Lucas, Zixing Wang and Yin Liu

    BMC Bioinformatics 2014 15(Suppl 7):S4

    Published on: 28 May 2014

  4. Research

    Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging

    The mitochondria are essential organelles and are the location of cellular respiration, which is responsible for the majority of ATP production. Each cell contains multiple mitochondria, and each mitochondrion...

    Perry G Ridge, Taylor J Maxwell, Spencer J Foutz, Matthew H Bailey, Christopher D Corcoran, JoAnn T Tschanz, Maria C Norton, Ronald G Munger, Elizabeth O'Brien, Richard A Kerber, Richard M Cawthon and John SK Kauwe

    BMC Bioinformatics 2014 15(Suppl 7):S6

    Published on: 28 May 2014

  5. Research

    Multistable switches and their role in cellular differentiation networks

    Cellular differentiation during development is controlled by gene regulatory networks (GRNs). This complex process is always subject to gene expression noise. There is evidence suggesting that commonly seen pa...

    Ahmadreza Ghaffarizadeh, Nicholas S Flann and Gregory J Podgorski

    BMC Bioinformatics 2014 15(Suppl 7):S7

    Published on: 28 May 2014

  6. Research

    Population substructure in Cache County, Utah: the Cache County study

    Population stratification is a key concern for genetic association analyses. In addition, extreme homogeneity of ethnic origins of a population can make it difficult to interpret how genetic associations in th...

    Aaron R Sharp, Perry G Ridge, Matthew H Bailey, Kevin L Boehme, Maria C Norton, JoAnn T Tschanz, Ronald G Munger, Christopher D Corcoran and John SK Kauwe

    BMC Bioinformatics 2014 15(Suppl 7):S8

    Published on: 28 May 2014

  7. Research

    Variant Tool Chest: an improved tool to analyze and manipulate variant call format (VCF) files

    Since the advent of next-generation sequencing many previously untestable hypotheses have been realized. Next-generation sequencing has been used for a wide range of studies in diverse fields such as populatio...

    Mark TW Ebbert, Mark E Wadsworth, Kevin L Boehme, Kaitlyn L Hoyt, Aaron R Sharp, Brendan D O'Fallon, John SK Kauwe and Perry G Ridge

    BMC Bioinformatics 2014 15(Suppl 7):S12

    Published on: 28 May 2014

  8. Research

    Yeast pheromone pathway modeling using Petri nets

    Our environment is composed of biological components of varying magnitude. The relationships between the different biological elements can be represented as a biological network. The process of mating in S. cerev...

    Abhishek Majumdar, Stephen D Scott, Jitender S Deogun and Steven Harris

    BMC Bioinformatics 2014 15(Suppl 7):S13

    Published on: 28 May 2014