Figure 8
Comparing the performance of Cyndi with 3 objectives and 4 objectives. Exemplary alignments of conformers generated by Cyndi with 3 and 4 objectives: (a) 1IF8 and (b) 1SME. Only the best-fitted conformers to the bioactive structures are shown. The crystal structure conformations are coloured in terms of element (Carbon in grey; oxygen in red and nitrogen in blue), the conformers generated by Cyndi with 3 objectives are coloured in magenta and the ones with 4 objectives are in green.