From: GLOSSI: a method to assess the association of genetic loci-sets with complex diseases
Type of permutation | Relative size of genes: out/in loci-set | Proportion of p-value < 0.05 | 95% CI |
---|---|---|---|
Phenotype | 50% | 0.052 | (0.038,0.066) |
100% | 0.053 | (0.039,0.067) | |
200% | 0.051 | (0.037,0.065) | |
Gene | 50% | 0.27 | (0.24,0.29) |
100% | 0.046 | (0.033,0.059) | |
200% | 0.004 | (0,0.008) |