Table 4 Power of the modified KS statistic when two genes in the reference set consist of a causal SNP
From: GLOSSI: a method to assess the association of genetic loci-sets with complex diseases
| Number of genes outside of loci-set | Relative size of genes: out/in loci-set | Proportion of p-value < 0.05 | |
|---|---|---|---|
| Scenario 17 | Scenario 18 | ||
| 50% | 0.464 | 0.842 | |
| 176 | 100% | 0.581 | 0.854 |
| 200% | 0.684 | 0.860 | |
| 50% | 0.371 | 0.804 | |
| 88 | 100% | 0.495 | 0.829 |
| 200% | 0.629 | 0.854 | |
| 50% | 0.145 | 0.683 | |
| 44 | 100% | 0.187 | 0.732 |
| 200% | 0.161 | 0.773 | |