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Table 4 Power of the modified KS statistic when two genes in the reference set consist of a causal SNP

From: GLOSSI: a method to assess the association of genetic loci-sets with complex diseases

Number of genes outside of loci-set

Relative size of genes: out/in loci-set

Proportion of p-value < 0.05

  

Scenario 17

Scenario 18

 

50%

0.464

0.842

176

100%

0.581

0.854

 

200%

0.684

0.860

 

50%

0.371

0.804

88

100%

0.495

0.829

 

200%

0.629

0.854

 

50%

0.145

0.683

44

100%

0.187

0.732

 

200%

0.161

0.773