Table 5 Loci-sets with unadjusted p-value no greater than 0.1% in the antihypertensive response example

Non-Hispanic white

   TPO signaling pathway

   Erk1/Erk2 Mapk signaling pathway

   Sprouty regulation of tyrosine kinase signals

   Multiple antiapoptotic pathways from IGF-1R signaling lead to bad phosphorylation

   PTEN pathway

   Transcription factor CREB and its extracellular signals

   Growth hormone signaling pathway

   PTEN dependent cell cycle arrest and apoptosis

   Upregulated in acute rejection transplanted kidney biopsies

   IL 3 signaling pathway

   Trka receptor signaling pathway

   IL-2 receptor beta chain in T cell activation

   B cell antigen receptor

   IL 4 receptor signaling in B lymphocytes

   Calcium signaling by HBx of Hepatitis B virus

   Glycogen processing

   IGF-1 signaling pathway

   Down regulated following Apc loss

   Liver selective

   TrkA receptor

   Inhibition of cellular proliferation by gleevec

   IL 6 signaling pathway

   Insulin signaling pathway

   Upregulated in fibroblasts following infection with human cytomegalovirus

   Down regulated by both curcumin and sulindac in SW260 colon carcinoma cells

   Upregulated by TPA in resistant HL-525 cells

African American

   Upregulated by UV-B light in epidermal keratinocytes

   Upregulated in well functioning transplanted kidney biopsies