ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble

Table 1 ProtSA solvent accessibilities of unfolded ensembles of test proteins

Protein PDB code	Number of residues	Accessibilities by ProtSA¹	Accessibilities by NACCESS²
[PDB:1LN4]	98	10520	10497
[PDB:1T1D]	100	11170	11136
[PDB:1BKR]	109	11683	11666
[PDB:1BGF]	124	13843	13808
[PDB:1JB3]	131	14300	14261
[PDB:2LIS]	136	15320	15302
[PDB:1QGV]	142	15648	15632
[PDB:1EY4]	149	16437	16430
[PDB:1EP0]	185	20568	20529
[PDB:1L3K]	196	21442	21436
[PDB:1BYI]	224	23476	23393
[PDB:1ES9]	232	25251	25250
[PDB:1II5]	233	25330	25258
[PDB:1WER]	334	37937	37845
[PDB:1FO9]	348	39539	39492
[PDB:1FCQ]	350	39941	39877
[PDB:1E5M]	416	43551	43429
[PDB:1GSO]	431	45765	45628
[PDB:2BCE]	579	62744	62631

¹Solvent accessibilities (in Å²) calculated with ProtSA, using ALPHASURF. They are averaged over 2000 unfolded structures of each protein. The first and the last five residues of each sequence are not taken into account.
²Solvent accessibilities (in Å²) calculated with NACCESS in otherwise identical conditions (taken from Table 3 in reference [14]).

ISSN: 1471-2105