Table 2 Top 10 pathway pairs showing significant differences in Z-transformed interaction scores in the lung cancer dataset.

NL

SCC

Cytokine Network (37)

TNF/Stress-Related Signaling (54)^§

7

0.97

0.56

13.8

Estrogen-responsive protein Efp controls cell cycle and breast tumor growth (24)

Propanoate_metabolism (26)

0

0.97

0.55

13.6

Activation of Src by Protein-tyrosine phosphatase alpha (22)

Nuclear_Receptors (51)

0

0.96

0.59

12.2

Double-Stranded RNA-Induced Gene Expression (15)

Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling (13)

0

0.96

0.56

11.8

Acute Myocardial Infarction (23)

Angiotensin-converting enzyme 2 regulates heart function (18)^§

11

0.96

0.60

11.5

ALK in cardiac myocytes (52)

Inositol_phosphate_metabolism (146)

0

0.96

0.61

11.4

p38 MAPK Signaling Pathway (69)

Apoptosis (73)^§

10

0.95

0.54

11.3

fMLP-induced chemokine gene expression in HMC-1 cells (62)^§

PTEN-dependent cell cycle arrest and apoptosis (25)

2

0.95

0.56

11.2

BRCA1-dependent Ub-ligase activity (18)

Aminosugars_metabolism (13)

0

0.96

0.61

11.2

Endocytotic role of NDK, Phosphins and Dynamin (21)

Pyruvate_metabolism (40)

0

0.96

0.65

11.0