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Table 2 Protein-protein interaction data sources incorporated in POINeT.

From: POINeT: protein interactome with sub-network analysis and hub prioritization

Data Source Version or Download Date Number of Interactions Included References References Details
BioGRID 2.0.37 202,244 Stark et al. (2006) Stark, C., Breitkreutz, B.J., Reguly, T., et al. (2006) BioGRID: a general repository for interaction datasets, Nucleic Acids Res, 34, D535–539.
IntACT 2008/2/11 121,560 Hermjakob et al. (2004) Hermjakob, H., Montecchi-Palazzi, L., Lewington, C., et al. (2004) IntAct: an open source molecular interaction database, Nucleic Acids Res, 32, D452–455.
HPRD version 7 37,107 Peri, S. et al. (2003) Peri, S. et al. (2003) Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Research. 13:2363–2371.
MPact 2005/12/22 12,955 Ulrich G. et al. (2006) Güldener U, Münsterkötter M, Oesterheld M, Pagel P, Ruepp A, Mewes HW, Stümpflen V(2006). MPact: the MIPS protein interaction resource on yeast. Nucl. Acids Res. 2006 34: D436–D441
DIP 2008/1/14 50,048 Xenarios et al. (2000) Xenarios, I., Rice, D.W., Salwinski, L., et al. (2000) DIP: the database of interacting proteins, Nucleic Acids Res, 28, 289–291.
MINT 4.0 99,773 Zanzoni et al. (2002) Zanzoni, A., Montecchi-Palazzi, L., Quondam, M., et al. (2002) MINT: a Molecular INTeraction database, FEBS Lett, 513, 135–140.
CYGD 2007/1/25 33,984 Guldener et al. (2005) Guldener, U., Munsterkotter, M., Kastenmuller, G., et al. (2005) CYGD: the Comprehensive Yeast Genome Database, Nucleic Acids Res, 33, D364–368.
BIND 2006/5/25 41,603 Bader et al. (2003) Bader, G.D., Betel, D. and Hogue, C.W. (2003) BIND: the Biomolecular Interaction Network Database, Nucleic Acids Res, 31, 248–250.
MIPS 2007/1/1 1,363 Mewes et al. (2004) Mewes, H.W., Amid, C., Arnold, R., et al. (2004) MIPS: analysis and annotation of proteins from whole genomes, Nucleic Acids Res, 32, D41–44.
  1. The numbers of PPIs from various data sources as collected by POINeT. The total number of PPIs is not the sum of all PPIs from various sources since there are numerous redundant entries.