Table 9 Distribution of conserved and not conserved CGIs over PBCs and gene association classes
From: Profile analysis and prediction of tissue-specific CpG island methylation classes
Conserved CGIs | ||||
|---|---|---|---|---|
Gene association class | Constitutively unmethylated (%)* | Constitutively methylated (%) | Unmethylated in sperm (%) | Differentially methylated (%) |
TSS | 75 (23.22) | 2 (2.38) | - | - |
Promoter | 43 (13.31) | 24 (28.57) | 8 (18.18) | 7 (15.91) |
3'UTR | 1 (0.31) | 2 (2.38) | 1 (2.27) | 3 (6.82) |
CDS | 12 (3.72) | 23 (27.38) | 7 (15.91) | 7 (15.91) |
Intron | 6 (1.86) | 3 (3.57) | - | 2 (4.55) |
Pseudogene | 18 (5.57) | 8 (9.52) | 7 (15.91) | 2 (4.55) |
NA | 2 (0.62) | 1 (1.19) | 2 (4.55) | 3 (6.82) |
Total # of conserved CGIs | 157 (48.61) | 63 (75.00) | 25 (56.82) | 24 (54.55) |
Not conserved CGIs | ||||
Gene association class | Constitutively unmethylated (%)* | Constitutively methylated (%) | Unmethylated in sperm (%) | Differentially methylated (%) |
TSS | 63 (19.50) | 1 (1.19) | 3 (6.82) | 2 (4.55) |
Promoter | 75 (23.22) | 4 (4.76) | 9 (20.45) | 8 (18.18) |
3'UTR | - | 4 (4.76) | - | 1 (2.27) |
CDS | 2 (0.62) | - | - | - |
Intron | 6 (1.86) | 5 (5.95) | - | 7 (15.91) |
Pseudogene | 15 (4.64) | 3 (3.57) | 7 (15.91) | 2 (4.55) |
NA | 5 (1.55) | 4 (4.76) | - | - |
Total # of not conserved CGIs | 166 (51.39) | 21 (25.00) | 19 (43.18) | 20 (45.45) |
Total # CGIs per PBC | 323 | 84 | 44 | 44 |