Table 5 Positive likelihood ratios for HIV-1 PR rules.
From: How to find simple and accurate rules for viral protease cleavage specificities
Rules used | Positive likelihood ratio | Sensitivity | Specificity |
|---|---|---|---|
HIVA1 | 11.3 | 31% | 97% |
HIVA1, HIVB1 | 6.2 | 41% | 93% |
HIVA1, HIVB1, HIVC1 | 5.2 | 57% | 89% |
HIVA1, HIVB1, HIVC1, HIVD1 | 4.7 | 61% | 87% |
HIVA1, HIVB1, HIVC1, HIVD1, HIVE1 | 4.7 | 64% | 86% |
HIVA2 | 11.3 | 33% | 97% |
HIVA2, HIVB2 | 6.8 | 40% | 94% |
HIVA2, HIVB2, HIVC2 | 5.6 | 44% | 92% |
HIVA2, HIVB2, HIVC2, HIVD2 | 5.2 | 48% | 91% |
HIVA2, HIVB2, HIVC2, HIVD2, HIVE2 | 4.5 | 49% | 89% |
Kontijevskis et al. [17] Fig. 1a | 2.1 | 3% | 99% |
Kontijevskis et al. [17] Fig. 1b | 1.7 | 87% | 49% |
Kontijevskis et al. [17] Table III | 0.8 | 3% | 97% |
Kontijevskis et al. [17] Table IV | 1.7 | 87% | 49% |
HIVcleave [37] | 45.4 | 2% | 100% |
HIVcleave [37] | 3.0 | 32% | 89% |
HIVcleave [37] | 2.8 | 50% | 82% |
L-SVM [38] | 29.1 | 2% | 100% |
L-SVM [38] | 10.6 | 31% | 97% |
L-SVM [38] | 6.7 | 50% | 93% |