From: BRNI: Modular analysis of transcriptional regulatory programs
Module Number | Main functions | Expression peak phase | *Transcription peak phase | Number of genes | Member genes that are known cell cycle regulators (TFs in bold) |
---|---|---|---|---|---|
1 | Histones (7/7) | S | M/G1 | 7 | |
2 | Cell wall (6/12); glycoproteins (3) | M/G1 | M | 12 | cig2,ams2 |
3 | Metabolism (6/12) | S/G2 | G1/S | 12 | |
4 | Cell wall (4/11), cell division (4/11) | M/G1 | G2/M | 11 | ace2, plo1, cdc15, slp1 |
5 | Mixed | S/G2 | G1/S | 10 | |
6 | Cytokinesis (2/9); | M/G1 | G2/M | 9 | fkh2 |
7 | Mixed | G1 | M | 27 | |
8 | Translation regulation (9/20) (ribosome biogenesis (7/20)); transporters (4/20) | G2 | G1/S | 20 | |
9 | Mixed | G2 | G1/S | 15 | |
10 | Mixed | Mixed | Mixed | 11 | |
11 | Mixed | G2/M | G2 | 15 | |
12 | Mixed | G1 | M | 15 | pmk1 |
13 | Mixed | M/G1 | M | 18 | cdc10, res2, csk1 |
14 | Mixed | G1/S | G1 | 18 | |
15 | Cell wall (6/21) | Early G2 | S/G2 | 21 | |
16 | Mixed | M | G2 | 27 | cdc13, crk1, cdr1, clb1 |