Skip to main content

Table 4 Assessment of SDPsite versions, diverse dataset.

From: Combining specificity determining and conserved residues improves functional site prediction

Family SDPsite
(λ = 0.5 AND λ = 1)
SDPsite
(λ = 0.5 OR λ = 1)
SDPsite (no SDPs)
PF00108 - - +
PF00128 - - +
PF00135 - - -
PF00215 + + -
PF00278 - + -
PF00293 + + +
PF00348 + + +
PF00351 - + +
PF00579 + + +
PF00583 - -* -
PF00590 + + -
PF00755 + + +
PF00871 + + +
PF00896 - + +
PF00962 - + +
PF01048 - + -
PF01112 - + -
PF01135 + + -
PF01202 - + +
PF01234 - + +
PF01467 -* - -*
PF01712 + + +
PF02274 + + +
PF03061 -* -* -
PF03171 + + -
PF03414 - + +
Accuracy 0.42 (11/26) 0.78 (20/26) 0.58 (15/26)
  1. '+': successful prediction (average distance to ligand <10 Å, p-value in Mann-Whitney test against all amino acids of the protein < 0.01), '-*': moderately successful prediction (average distance to ligand <10 Å, p-value in Mann-Whitney test against all amino acids of the protein < 0.1), '-' otherwise.