BMC Bioinformatics

Table 6 Assessment of SDPsite versions, homogeneous dataset.

From: Combining specificity determining and conserved residues improves functional site prediction

Family	SDPsite (λ = 0.5 AND λ = 1)	SDPsite (λ = 0.5 OR λ = 1)	SDPsite (no SDPs)
PF00303	-	-	+
PF00693	-	+	-
PF00925	-	-	+
PF01014	+	+	+
PF01227	+	+	-
PF01293	-	-	+
PF01583	-	-	+
PF01656	+	+	+
PF01702	+	+	-
PF01747	+	+	+
PF02110	+	+	+
PF02223	+	+	+
PF02277	+	+	+
PF02353	+	+	-
PF02569	+	+	+
PF02898	-	+	-
PF02901	+	+	-
PF03332	-	+	-
Accuracy	0.61 (11/18)	0.78 (14/18)	0.55 (10/18)

'+': successful prediction (average distance to ligand <10 Å, p-value in Mann-Whitney test against all amino acids of the protein < 0.01), '-' otherwise.

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