Figure 5
Comparisons between predicted and actual structures. The left column depicts the actual structures of molecules as verified chemically while the right column depicts the closest prediction from NP.searcher. Most unknown polyketide or peptide units, as seen in the cryptophycin example, result from novel signature sequences that do not match well with any specificity codes from our database of specificity codes compiled from literature sources. The actual chemical moieties are color-coded blue while the predicted or unrecognized moieties are shown in red.