Automated genome mining for natural products

BMC Bioinformatics

Table 1 Validation of PKS domain recognition

	Co-linear/Non-co-linear Genes	AT^a	KR^b	DH^c	ER^d
Ratio	23/39	309/333	291/293	159/177	59/60
Percentage (%)	59.0	92.8	99.3	89.8	98.3

^a AT, acyltransferase. ^b KR, ketoreductase. ^c DH, dehydrogenase. ^d ER, enoylreductase.
Highly unique PKS sequences that did not align with database-derived PKS AT, KR, DH, and ER sequences using BLAST resulted in some false negatives.

ISSN: 1471-2105