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Table 2 Validation of NRPS domain recognition

From: Automated genome mining for natural products

 

Co-linear/Non-co-linear Genes

Aa/Total # of A domains

Eb domains detected/Total # of E domains

Ratio

32/40

208/254

30/39

Percentage (%)

80.0

81.9

76.9

  1. a A, adenylation. b E, epimerization.
  2. Highly unique NRPS sequences that did not align with database-derived NRPS A and E sequences using BLAST resulted in some false negatives.