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Figure 5 | BMC Bioinformatics

Figure 5

From: The development of a comparison approach for Illumina bead chips unravels unexpected challenges applying newest generation microarrays

Figure 5

Comparison of rank correlation of probes between subsequent array versions. Rank correlation was used as a metric to investigate comparability of hybridization results between the two array versions. In a first step only moderately to highly expressed probes (signal intensity > 500) were used for comparison. This analysis was performed for (A) identical oligonucleotides in the Treg data set, (B) cross-annotated probes in the Treg data set, (C) identical oligonucleotides in the whole blood data set, and (D) cross-annotated probes in the whole blood data set. In the second step all probes which were present in either one of the sub-groups were used. Again, this analysis was performed for (E) identical oligonucleotides in the Treg data set, (F) cross-annotated probes in the Treg data set, (G) identical oligonucleotides in the whole blood data set, and (H) cross-annotated probes in the whole blood data set.

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