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Table 1 Parameter values for ATM and p53 module

From: Modeling the role of p53 pulses in DNA damage- induced cell death decision

ATM module p53-MDM2 module
k1 = 1 min-1 katm' = 0.01 s-1
k2 = 0.01 μM kmd' = 0.03 min-1
k3 = 0.005 min-1 δp53 = 0.01 min-1
k4 = 2.5 min-1 δMDM2 = 0.002 min-1
k5 = 1 Ka = 0.3 μM
k6 = 0.1 min-1 Kb = 0.3 μM
k7 = 0.5 μM Kc = 0.3 μM
k8 = 1 min-1 Kd = 0.5 μM
k9 = 0.01 μM Ke = 0.5 μM
k10 = 0.005 min-1 kind = 0.02 μM·min-1
k11 = 0.8 μM·min-1 ktrans = 0.1 μM·min-1
k12 = 0.1 μM μp53 = 0.003 μM·min-1
k13 = 0.02 μM-1·min-1 μMDM2 = 0.002 μM·min-1
[ATM]total = 1 μM m = 4
[MRN]total = 1 μM n = 3 np = 3