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Table 5 Gavin06MATRIX PPI-SDDI-PPI triangles and Krogan06 PPI-SDDI-PPI triangles: Gene Ontology (GO) similarities and correlations.

From: Triangle network motifs predict complexes by complementing high-error interactomes with structural information

 

Correlation

Gavin06MATRIX

Correlation

Krogan06

GO Functional similarity

Average over protein pairs in SDDI edges

0.48

0.37

Average over protein pairs in PPI edges

0.18 and 0.18

0.35 and 0.36

PPI-PPI similarity correlation coefficient

0.88

0.76

SDDI-PPI similarity correlation coefficient

0.16 and 0.18

0.58 and 0.59

GO Process/Location similarity

Average over protein pairs in SDDI edges

0.71

0.67

Average over protein pairs in PPI edges

0.28 and 0.27

0.67 and 0.67

PPI-PPI similarity correlation coefficient

0.97

0.6

SDDI-PPI similarity correlation coefficient

0.08 and 0.09

0.46 and 0.45

  1. Often, the two PPIs of a triangle have close GO functional/process/location similarity.