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Table 1 SIMU2, true positives (TP) and false positives (FP) in simulations with dependent base.

From: Detecting intergene correlation changes in microarray analysis: a new approach to gene selection

Effect Size

CV Method

WRS Method

 

FP mean(STD)

TP mean(STD)

FP mean(STD)

TP mean(STD)

0.1

0.25(0.7)

0.1(0.3)

0.05(0.22)

0.0(0.0)

0.2

0.9(2.39)

1.2(4.79)

0.15(0.48)

0.05(0.22)

0.3

1.1(3.51)

4.9(10.77)

0.15(0.48)

0.2(0.87)

0.4

0.9(3.48)

80.5(25.79)

0.65(1.35)

0.0(0.0)

  1. In CV method with effect size 0.4, the TP drops to 2.9(6.82) without Fisher transformation.
  2. Total number of genes: 708. Number of differentially correlated genes: 100. Method: group method. Extended Bonferroni threshold: 1.0.