Figure 5

Projection of potential subsites onto the representative structures of families in prediction testset. Potential subsites commonly identified by three methods, SPEER, GroupSim, and MultiRELIEF are mapped onto representative structures from the following families: a) ADP specific phosphofructokinase/glucokinase family (1U2X); b) DUF498/DUF598 domain family (1IHN); c) guanine nucleotide exchange factor (GEF)-Ras like GTPases family (1NVX); d) p21-Rho binding domain family (1CEE); e) Raf-like Ras-binding domain family (1C1Y) and f) Ras association (RalGDS/AF-6) domain (1LFD) family. Commonly predicted C3 and C2 sites are colored in green and blue, respectively. The figure was generated using the PyMOL software [23].