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Figure 8 | BMC Bioinformatics

Figure 8

From: Linked region detection using high-density SNP genotype data via the minimum recombinant model of pedigree haplotype inference

Figure 8

The simulated grand-paternal haplotype allele sharing status among all members, excluding grandmother. Each individual has two haplotypes, paternal haplotype and maternal haplotype. Note that individual D is the founder of the disease in the family. The two haplotypes of individual D are shown as 1-th haplotype and 0-th haplotype at the top and at the bottom, respectively. Any other individual may inherit alleles from both 0-th haplotype and 1-th haplotype of individual D. Thus, any other individual in the family appears twice (upper part and lower part) in the figure. The upper part shows the segments inherited from the 1-th haplotype of D and the lower part shows the segments inherited from the 0-th haplotype of D. The segments from diseased individuals are red and the segments from normal individuals are blue. The simulated (true) linked region is indicated by the horizontal black double-direction arrow in the middle.

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BMC Bioinformatics

ISSN: 1471-2105

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