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Table 10 Comparison with Merlin using Affymetrix 50 K GeneChips.

From: Linked region detection using high-density SNP genotype data via the minimum recombinant model of pedigree haplotype inference

 

Run time (s)

overlap/real

overlap/found

0+3

16.717 (0.898)

0.941 (0.805)

0.605 (0.862)

0+4

23.325 (1.126)

0.928 (0.824)

0.594 (0.930)

0+5

30.634 (1.746)

0.941 (0.901)

0.587 (0.936)

0+6

39.028 (3.901)

0.987 (0.929)

0.576 (0.969)

2+3(4 bits)

3.276 (1.340)

1.000 (0.928)

0.960 (1)

2+4(6 bits)

4.596 (1.735)

0.9997 (0.937)

0.967 (0.990)

P5(7 bits)

7.714 (2.325)

0.999 (0.933)

0.919 (0.979)

P9(9 bits)

7.365 (3.255)

0.999 (0.879)

0.926 (0.958)

P10(11 bits)

19.15 (8.829)

0.999 (0.797)

0.912 (0.968)

P11(12 bits)

11.37 (14.01)

1.000 (0.938)

0.924 (0.979)

P12(13 bits)

25.62 (31.57)

1.000 (0.922)

0.842 (0.958)

P7(14 bits)

13.58 (58.14)

1.000 (0.949)

0.933 (0.990)

P15(14 bits)

46.96 (43.15)

1.000 (0.906)

0.894 (0.979)

P13(15 bits)

23.72 (1282.05)

1.000 (0.970)

0.875 (1)

P16(15 bits)

37.93 (384.78)

0.988 (0.950)

0.877 (0.990)

P14(16 bits)

15.042 (NA)

1.000 (NA)

0.927 (NA)

P6(17 bits)

40.754 (NA)

1.000 (NA)

0.869 (NA)

  1. Each cell contains two values. The first one is by our program and the one in brackets is by Merlin. Pedigree 0+i for i = 3, 4, 5 and 6 stands for a nuclear family with i children and the genotype data for parents is not available. Pedigree 2+i for i = 3 and 4 stands for a nuclear family with i children and the genotype data for both parents is available. "NA" means that the program failed to execute on this pedigree.