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Table 5 Inferred true proportions of target genes of Ste12 under the pseudohyphal condition in S. cerevisiae and S. mikatae.

From: Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data

 

FNR

 

0.20

0.25

0.30

0.35

0.40

FPR = 0.001

0.956

0.954

0.953

0.952

0.950

 

0.006

0.005

0.003

0.002

0.001

 

0.015

0.014

0.013

0.012

0.011

 

0.023

0.026

0.030

0.034

0.038

 

0.20

0.25

0.30

0.35

0.40

FPR = 0.002

0.958

0.957

0.956

0.954

0.953

 

0.005

0.004

0.002

0.001

0

 

0.014

0.013

0.012

0.011

0.010

 

0.023

0.026

0.030

0.034

0.038

 

0.20

0.25

0.30

0.35

0.40

FPR = 0.003

0.961

0.960

0.958

0.957

0.955

 

0.003

0.002

0.001

0

0

 

0.012

0.012

0.011

0.010

0.008

 

0.024

0.026

0.030

0.033

0.037

 

0.20

0.25

0.30

0.35

0.40

FPR = 0.004

0.964

0.962

0.961

0.959

0.957

 

0

0

0

0

0

 

0.011

0.010

0.009

0.008

0.007

 

0.024

0.026

0.029

0.032

0.036

 

0.20

0.25

0.30

0.35

0.40

FPR = 0.005

0.966

0.965

0.963

0.961

0.959

 

0

0

0

0

0

 

0.10

0.009

0.008

0.007

0.006

 

0.024

0.026

0.029

0.032

0.035

  1. For different values of false positive and false negative rates, the four inferred proportions of the target genes of Ste12 under the pseudohyphal condition in S. cerevisiae and S. mikatae are tabulated. The observed vector of proportions is (0.959, 0.010, 0.017, 0.015)t.