Skip to main content
Figure 5 | BMC Bioinformatics

Figure 5

From: CLEAN: CLustering Enrichment ANalysis

Figure 5

Differences in the reproducibility of CLEAN and cwCLEAN scores. Improvements in the reproducibility of CLEAN over cwCLEAN scores were demonstrated by box plots of differences in correlation coefficients, and odds ratios and p-values in 2-by-2 contingency tables of statistically significant scores. A) Box plots of differences in correlations between CLEAN and cwCLEAN scores of all 6 pairs of breast cancer datasets for three different clustering algorithms. Since all differences are positive, this indicates that the correlation coefficient was higher for CLEAN scores in each of the 6 pairs. B) Box plots of differences in odds ratios for 2-by-2 contingency tables of statistically significant CLEAN and cwCLEAN scores for all 6 pairs of breast cancer datasets and three different clustering algorithms. All differences are positive implicating higher reproducibility of CLEAN scores. C) Box plots of differences in the statistical significances in (-log10(p-values)) in the Fisher's Exact test for the same contingency tables as in B). The fact that all differences are positive again implicates higher reproducibility of CLEAN scores.

Back to article page