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Table 1 Top significant GO groups identified between BCR/ABL and NEG phenotypes for the ALL dataset.

From: Improving detection of differentially expressed gene sets by applying cluster enrichment analysis to Gene Ontology

No

GO ID

Term

Ranka

p-value

1

GO:0043122

regulation of I-kappaB kinase/NF-kappaB ...

3

3.7e-06

 

GO:0043123

positive regulation of I-kappaB kinase/N...

-

 
 

GO:0043124

negative regulation of I-kappaB kinase/N...

-

 

2

GO:0000084

S phase of mitotic cell cycle

-

2.9e-05

 

GO:0000115

S-phase-specific transcription in mitoti...

-

 

3

GO:0032715

negative regulation of interleukin-6 pro...

-

0.012

 

GO:0032755

positive regulation of interleukin-6 pro...

-

 
 

GO:0042226

interleukin-6 biosynthetic process

-

 
 

GO:0045408

regulation of interleukin-6 biosynthetic...

-

 
 

GO:0045410

positive regulation of interleukin-6 bio...

-

 

4

GO:0032088

inhibition of NF-kappaB transcription fa...

-

0.027

 

GO:0043392

negative regulation of DNA binding

-

 
 

GO:0043433

negative regulation of transcription fac...

-

 

5

GO:0007257

activation of JNK activity

-

0.045

 

GO:0043507

positive regulation of JNK activity

-

 
  1. a Refers to the rank on the list of top GO terms enriched by individual GO term analysis for FDR controlled at 5%. The dash (-) indicates that this GO term was not found on the list generated by individual GO term analysis.