From: Accurate and fast methods to estimate the population mutation rate from error prone sequences
Evolutionary simulations | Coalescent/mutation models | Watterson and Tajima estimators | |||||||
---|---|---|---|---|---|---|---|---|---|
θ | n | ε | θ FW | θ KM | θ' KM | θ W | θ' W | θ T | θ' T |
A1: 1 | 8 | 0.0 | 0.96 ± 0.10 | 0.76 ± 0.10 | 1.10 ± 0.15 | 0.98 ± 0.10 | 1.12 ± 0.16 | 1.02 ± 0.12 | 1.10 ± 0.15 |
A2: 1 | 8 | 0.5 | 3.49 ± 0.23 | 0.90 ± 0.14 | 0.96 ± 0.15 | 2.63 ± 0.1 5 | 0.94 ± 0.15 | 2.04 ± 0.13 | 0.95 ± 0.16 |
A3: 1 | 16 | 0.0 | 1.02 ± 0.10 | 0.84 ± 0.09 | 1.01 ± 0.12 | 1.00 ± 0.09 | 0.99 ± 0.11 | 0.97 ± 0.10 | 0.96 ± 0.12 |
A4: 1 | 16 | 0.5 | 5.10 ± 0.28 | 0.99 ± 0.12 | 1.02 ± 0.13 | 3.43 ± 0.16 | 1.03 ± 0.13 | 2.01 ± 0.13 | 1.01 ± 0.13 |
B1: 2 | 8 | 0.0 | 1.92 ± 0.17 | 1.51 ± 0.17 | 1.80 ± 0.25 | 1.92 ± 0.18 | 1.81 ± 0.25 | 1.89 ± 0.20 | 1.82 ± 0.26 |
B2: 2 | 8 | 0.5 | 4.38 ± 0.26 | 1.80 ± 0.20 | 1.92 ± 0.26 | 3.44 ± 0.19 | 1.91 ± 0.26 | 2.91 ± 0.20 | 1.92 ± 0.25 |
B3: 2 | 16 | 0.0 | 2.06 ± 0.16 | 1.78 ± 0.15 | 2.02 ± 0.19 | 2.04 ± 0.16 | 2.04 ± 0.20 | 2.09 ± 0.19 | 2.10 ± 0.22 |
B4: 2 | 16 | 0.5 | 6.19 ± 0.33 | 1.88 ± 0.17 | 1.92 ± 0.19 | 4.32 ± 0.20 | 1.92 ± 0.19 | 2.95 ± 0.20 | 1.96 ± 0.22 |
C1: 4 | 8 | 0.0 | - | - | 4.05 ± 0.44 | 4.27 ± 0.35 | 4.27 ± 0.53 | 4.31 ± 0.39 | 4.32 ± 0.54 |
C2: 4 | 8 | 0.5 | - | - | 3.89 ± 0.46 | 5.62 ± 0.33 | 4.09 ± 0.53 | 5.12 ± 0.38 | 4.13 ± 0.54 |
C3: 4 | 16 | 0.0 | - | - | 4.00 ± 0.31 | 4.12 ± 0.28 | 4.21 ± 0.38 | 4.24 ± 0.36 | 4.28 ± 0.41 |
C4: 4 | 16 | 0.5 | - | - | 3.82 ± 0.31 | 6.23 ± 0.27 | 3.87 ± 0.35 | 4.84 ± 0.32 | 3.86 ± 0.38 |
D1: 8 | 8 | 0.0 | - | - | 7.88 ± 0.71 | 7.75 ± 0.49 | 7.87 ± 0.78 | 7.78 ± 0.55 | 7.85 ± 0.77 |
D2: 8 | 8 | 0.5 | - | - | 7.90 ± 0.85 | 9.67 ± 0.63 | 8.38 ± 1.03 | 9.22 ± 0.73 | 8.39 ± 1.03 |
D3: 8 | 16 | 0.0 | - | - | 7.82 ± 0.54 | 8.08 ± 0.49 | 8.20 ± 0.72 | 8.26 ± 0.69 | 8.32 ± 0.82 |
D4: 8 | 16 | 0.5 | - | - | 8.00 ± 0.58 | 10.73 ± 0.52 | 8.31 ± 0.71 | 9.57 ± 0.68 | 8.60 ± 0.81 |