Figure 3
From: Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology
Genome scan of the cattle genome Bos Taurus. A plot of the number of repair proteins as a function of methodology threshold. Despite different technique formulations, both BLAST and SVM (Method P) show an exponential decrease in the number of proteins likely to be related to DNA repair as the decision threshold is tightened. The BLAST approach has had e-values adjusted to fit in the graph. At a Method P threshold of 0.151 which resulted in no false positives and 57% true positives in GO-PDB identification experiments, several proteins of unknown function are predicted to be DNA repair related.