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Table 5 Classification: Double Strand Break Repair

From: Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology

Seq. Similarity Pos/Neg
(% Pos)
Method AUC TPR-0 TPR-1% TPR-5%
   P 0.82 9.77 24.71 40.23
   PS 0.89 25.86 54.02 66.67
50% 174/1656
(10%)
PF 0.80 9.77 17.82 35.63
   BLAST 0.88 15.52 64.37 73.56
   PH 0.83 5.75 17.82 47.70
   PSH 0.89 1.72 25.29 64.94
   P 0.92 16.92 55.64 71.05
   PS 0.94 27.44 69.92 77.82
90% 266/4379
(6%)
PF 0.90 27.44 46.62 67.29
   BLAST 0.92 13.53 76.69 83.08
   PH 0.89 0.38 19.92 40.23
   PSH 0.93 7.14 34.59 67.67
   P 0.94 26.65 63.19 75.82
   PS 0.94 34.62 73.90 83.24
0% 364/6983
(5%)
PF 0.91 26.65 58.24 69.51
   BLAST 0.93 0.00 78.30 86.81
   PH 0.87 2.47 10.71 29.12
   PSH 0.93 2.75 29.12 60.71
  1. Experiments using Double Strand Break repair (GO:0006302) as the type of protein to identify. "Pos/Neg" shows the number of DSB repair-related and non-related proteins for a particular sequence similarity.