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Table 7 Classification: Regulation of DNA Repair

From: Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology

Seq. Similarity Pos/Neg
(% Pos)
Method AUC TPR-0 TPR-1% TPR-5%
   P 0.97 57.02 92.98 94.74
   PS 0.98 87.72 93.86 95.61
50% 114/1716
(6%)
PF 0.96 51.75 92.11 93.86
   BLAST 0.96 85.96 94.74 94.74
   PH 0.99 50.88 93.86 97.37
   PSH 0.99 76.32 93.86 97.37
   P 0.98 62.64 94.83 97.13
   PS 0.99 90.80 95.40 97.70
90% 174/4471
(4%)
PF 0.97 52.30 93.68 94.83
   BLAST 0.99 82.76 97.13 97.13
   PH 0.99 62.07 97.13 98.28
   PSH 0.99 83.33 95.98 97.70
   P 0.99 69.70 97.35 98.48
   PS 0.99 88.26 96.97 99.24
0% 264/7083
(4%)
PF 0.99 36.74 95.83 97.35
   BLAST 0.99 21.97 98.48 98.48
   PH 0.99 36.74 98.86 99.24
   PSH 0.99 80.68 98.11 99.24
  1. Experiments using "Regulation of DNA repair" (GO:0006282) as the type of protein to identify. "Pos/Neg" shows the number of regulation-related and non-related proteins for a particular sequence similarity.