Figure 3
From: Integrative modeling of transcriptional regulation in response to antirheumatic therapy
Reconstructed gene regulatory network of genes up- or down-regulated during first week of therapy. The TILAR algorithm used gene expression data and transcription factor binding predictions to infer a network of 84 TF-gene and 22 gene-TF interactions. The size of the nodes corresponds to their degree of connectivity. Three parts of the network model are shown in detail in figure 5. The full model is available as a Cytoscape session file of (additional file 5).