Figure 6

ROC curves for the benchmarking gene regulatory network. The better a method performs, the closer its curve will be to the upper-left corner. The black curve represents the rating of our method when including 54 of 67 predicted TF-gene interactions. Remarkably, TILAR not only outperforms CLR, ARACNE, GeneNet and the conventional Lasso, but can also be combined with the adaptive LARS if adequate prior knowledge on gene-TF interactions is available. Using both techniques in combination we could infer gene-gene relationships more reliably.