Table 1 Positive set PPIs for the SVM-based method. a
From: Assessing the druggability of protein-protein interactions by a supervised machine-learning method
PPI | PPI | ||
|---|---|---|---|
Protein 1 | Protein 2 | Protein 1 | Protein 2 |
ARF1 | CYTH1 b | GRB2 | EGFR |
ARF1 | CYTH1 b | GRB2 | MET |
ARF1 | CYTH2 c | HOXB1 | PBX1 |
ARF1 | CYTH2 c | IL1B | IL1R1 |
BCL2 | BAK1 | IL2 | IL2RA |
BCL2L1 | BAK1 | MAGI3 | PTEN |
BIRC4 | CASP3 | MDM2 | TP53 |
BIRC4 | CASP9 | PIK3R1 | PDGFRB |
BIRC4 | DIABLO | RAC1 | TIAM1 |
BIRC5 | BIRC5 | RAC1 | TRIO |
CALM1 | CAMK1 | STAT3 | STAT3 |
CALM1 | MYLK | TCF7L1 | CTNNB1 |
CALM1 | PDE1A | TCF7L2 | CTNNB1 |
CD4 | HLA-DQB1 | THRB | NCOA2 |
ESR1 | NCOA2 | TNF | TNF |
FKBP1A | TGFBR1 | ZAP70 | CD247 |