PhyloLoc and GOLoc architecture. The architectures of PhyloLoc and GOLoc from MultiLoc2-LowRes. The input of PhyloLoc is a vector of similarities (phylogenetic profile) between the query sequence and the best sequence match in each genome inferred from BLAST. The input of GOLoc is a binary-coded vector representing the GO terms of the query sequence inferred from InterPro using InterProScan. PhyloLoc and GOLoc use one-versus-one SVMs to process their input and to calculate probability estimates for each localization.