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Table 2 Comparison of the localization-specific prediction results using BaCalLo independent dataset (BacelLo IDS)

From: MultiLoc2: integrating phylogeny and Gene Ontology terms improves subcellular protein localization prediction

   Animals Fungi Plants
Predictor Loc No. SE SP MCC No. SE SP MCC No. SE SP MCC
MultiLoc2-LowRes SP 75 97 97 0.89 9 78 98 0.60 6 83 95 0.58
  mi 48 89 97 0.81 77 68 94 0.62 6 67 96 0.51
  ch - - - - - - - - 72 77 94 0.72
  nu 224 62 93 0.57 152 63 79 0.36 36 91 90 0.77
  cy 85 72 82 0.43 180 54 78 0.27 17 41 94 0.38
  nu/cy 308 93 96 0.87 332 92 78 0.63 52 94 92 0.84
MultiLoc2-HighRes SP 75 87 95 0.79 9 78 98 0.63 6 83 93 0.50
  mi 48 83 96 0.75 77 51 95 0.52 6 67 93 0.40
  ch - - - - - - - - 72 53 94 0.51
  nu 224 58 93 0.54 152 50 84 0.32 36 86 91 0.74
  cy 85 71 80 0.39 180 56 75 0.22 17 37 87 0.20
  nu/cy 308 91 91 0.78 332 84 76 0.48 52 93 84 0.74
BaCelLoc SP 75 93 97 0.88 9 100 98 0.74 6 100 95 0.66
  mi 48 74 95 0.66 77 79 87 0.58 6 17 100 0.40
  ch - - - - - - - - 72 71 83 0.54
  nu 224 57 83 0.41 152 72 67 0.38 36 88 78 0.60
  cy 85 51 74 0.21 180 32 84 0.19 17 27 98 0.38
  nu/cy 308 93 92 0.83 332 85 83 0.61 52 88 84 0.70
LOCtree SP 75 79 91 0.65 9 78 92 0.35 6 83 96 0.60
  mi 48 64 92 0.51 77 42 92 0.38 6 58 90 0.30
  ch - - - - - - - - 72 77 88 0.66
  nu 224 66 73 0.39 152 63 59 0.22 36 72 89 0.61
  cy 85 35 86 0.22 180 35 78 0.15 17 33 97 0.39
  nu/cy 308 84 83 0.64 332 83 49 0.31 52 75 93 0.70
Protein Prowler SP 75 86 99 0.88 9 93 99 0.20 6 100 92 0.61
  mi 48 51 99 0.71 77 33 99 0.51 6 67 86 0.40
  ch - - - - - - - - 72 7 95 0.40
  nu/cy 308 98 73 0.79 332 98 40 0.52 52 86 77 0.52
TargetP SP 75 88 98 0.88 9 89 97 0.56 6 100 93 0.61
  mi 48 82 92 0.63 77 50 92 0.44 6 50 91 0.26
  ch - - - - - - - - 72 55 91 0.49
  nu/cy 308 89 89 0.75 332 89 59 0.48 52 83 79 0.62
WoLF PSORT SP 75 92 94 0.80 9 89 99 0.73 6 33 95 0.24
  mi 48 71 95 0.63 77 53 90 0.44 6 42 99 0.52
  ch - - - - - - - - 72 61 81 0.43
  nu 224 77 81 0.58 152 93 39 0.35 36 72 83 0.52
  cy 85 34 88 0.23 180 11 98 0.19 17 24 83 0.28
  nu/cy 308 89 90 0.76 332 89 57 0.46 52 87 74 0.61
  1. The sensitivity (SE) and specificity (SP), given in percentages, and Matthews correlation coefficient (MCC) are listed for each localization (Loc). The number of clusters (No.) per localization is also shown. In Protein Prowler and TargetP, predictions for nu and cy are only available grouped as nu/cy.