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Table 3 Results of simulation study: Fisher's exact test.

From: Comparative study of gene set enrichment methods

 

α= 0.01

α= 0.02

α= 0.03

α= 0.04

α= 0.05

 

P-value

P-value

P-value

P-value

P-value

 

mean

se

mean

se

mean

se

mean

se

mean

se

1

0.4117

0.0901

0.2789

0.0773

0.1509

0.0411

0.1243

0.0406

0.1137

0.0427

2

0.1961

0.0795

0.0342

0.0171

0.0270

0.0217

0.0287

0.0265

0.0140

0.0120

3

0.0085

0.0033

0.0019

0.0011

0.0024

0.0010

0.0034

0.0020

0.0053

0.0034

4

0.0030

0.0017

0.0016

0.0006

0.0039

0.0018

0.0081

0.0037

0.0113

0.0039

5

2e-04

0.0002

1e-06

0

1e-06

0

6e-07

0

7e-07

0

  1. P-values for the first gene set in the five different scenarios (rows) described in the text. In each column we report the significance level (α) adopted in t-test to find DE genes.