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Table 2 Predicted subcellular distribution of human hypothetical proteins

From: In Silico screening for functional candidates amongst hypothetical proteins

Compartment Predicted subcellular distribution 2006 dataset (5860 proteins) Predicted subcellular distribution 2008 dataset of hypothetical proteins (1455 proteins)
Nucleus 37% 36%
Cytoplasm 13% 14%
Plasma membrane 12% 8%
Lysosomes 9% 9%
Golgi 9% 11%
Peroxysomes 7% 10%
Extracellular/Secretory 6% 4%
Mitochondria 5% 5%
Endoplasmic reticulum 2% 3%
  1. The protein localization prediction program pTarget was used to predict the subcellular localization of 5860 and 1455 hypothetical proteins from the 2006 and 2008 datasets respectively.