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Table 11 Prediction accuracy of the best MDR model constructed from the 2LOmb output.

From: Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses

Description

Value

SNP and Gene

rs2269241 (PGM1), rs3790857 (PGM1), rs1893551 (PARK2), rs6924502 (PARK2), rs1871142 (GYS2), rs10770836 (GYS2)

Classification (Training) Accuracy

0.5709

Prediction Accuracy

0.5402

Cross-Validation Consistency (CVC)

9/10

  1. The model contains six SNPs from PGM1, PARK2 and GYS2. A permutation test with 1,000 randomised replicates of case-control data for this model reveals that the empirical p-value for the null hypothesis of no association is p < 0.001.
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BMC Bioinformatics

ISSN: 1471-2105

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