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Table 13 Penetrances for a two-locus interaction model.

From: Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses

 

Penetrance of Genotype

 

Genotype

BB

Bb

bb

Marginal Penetrance

AA

f 00

f 01

f 02

M A 0

Aa

f 10

f 11

f 12

M A 1

aa

f 20

f 21

f 22

M A 2

Marginal Penetrance

M B 0

M B 1

M B 2

K

  1. f ij is the disease penetrance of genotype ij. M Ai and M Bj are the marginal penetrances for genotype i at locus A and genotype j at locus B, respectively. M Ai = M Bj = K, ∀i, j ∈ {0, 1, 2} in a pure epistasis model.
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BMC Bioinformatics

ISSN: 1471-2105

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