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Table 17 Disease prevalence that gives the target maximum heritability of 0.01, 0.025 and 0.05 for two-, three- and four-locus interaction models.

From: Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses

 

Prevalence (K)

Model

(K) = 0.01

(K) = 0.025

(K) = 0.05

Two-locus

0.004975

0.012346

0.024390

Three-locus

0.001110

0.002770

0.005525

Four-locus

0.000286

0.000714

0.001427