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Table 5 Genotype relative risk evaluated from genotype distribution of SNPs in LMX1A.

From: Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses

  

Frequency

  

SNP

Genotype

Case

Control

Relative Risk

95% CI

SNP5

0

0.8429

0.8642

0.9754

(0.9526-0.9987)

 

1

0.1531

0.1315

1.1642

(1.0140-1.3366)

 

2

0.0040

0.0043

0.9248

(0.3840-2.2271)

SNP6

0

0.8799

0.8492

1.0362

(1.0135-1.0594)

 

1

0.1161

0.1465

0.7924

(0.6829-0.9193)

 

2

0.0040

0.0043

0.9248

(0.3840-2.2271)

(SNP5, SNP6)

00

0.8329

0.8299

1.0036

(0.9784-1.0295)

 

01

0.0100

0.0343

0.2918

(0.1814-0.4695)

 

10

0.0470

0.0193

2.4355

(1.7644-3.3618)

 

11

0.1061

0.1119

0.9482

(0.8061-1.1153)

 

22

0.0040

0.0040

1.0018

(0.4103-2.4465)

  1. The explanation for how the relative risks are obtained and displayed is the same as that given in Table 3. The major/minor alleles for rs2348250 and rs6702087 are G/A and G/C, respectively. The allelic information is extracted from the original T2D data. SNP5 = rs2348250 and SNP6 = rs6702087.