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Table 7 Genotype relative risk evaluated from genotype distribution of SNPs in PARK2.

From: Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses

  

Frequency

  

SNP

Genotype

Case

Control

Relative Risk

95% CI

SNP7

0

0.4802

0.5110

0.9398

(0.8873-0.9954)

 

1

0.4322

0.4041

1.0695

(1.0008-1.1429)

 

2

0.0875

0.0849

1.0313

(0.8581-1.2395)

SNP8

0

0.4892

0.4923

0.9937

(0.9380-1.0527)

 

1

0.4087

0.4121

0.9917

(0.9267-1.0613)

 

2

0.1021

0.0955

1.0682

(0.9009-1.2665)

(SNP7, SNP8)

00

0.4492

0.4844

0.9275

(0.8726-0.9858)

 

01

0.0285

0.0260

1.0982

(0.7841-1.5380)

 

02

0.0025

0.0007

3.7569

(0.7296-19.3450)

 

10

0.0400

0.0080

5.0092

(3.1856-7.8767)

 

11

0.3792

0.3848

0.9854

(0.9169-1.0590)

 

12

0.0130

0.0113

1.1492

(0.6918-1.9089)

 

21

0.0010

0.0013

0.7514

(0.1378-4.0984)

 

22

0.0865

0.0836

1.0358

(0.8606-1.2465)

  1. The explanation for how the relative risks are obtained and displayed is the same as that given in Table 3. The major/minor alleles for rs1893551 and rs6924502 are G/A and T/C, respectively. The allelic information is extracted from the original T2D data. SNP7 = rs1893551 and SNP8 = rs6924502.
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BMC Bioinformatics

ISSN: 1471-2105

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