Figure 2
From: RCMAT: a regularized covariance matrix approach to testing gene sets
Cumulative distribution function of RCMAT nominal p-values under several simulated non-null conditions. Under each of 12 selected conditions 100 simulation experiments were performed and permutation p-values obtained. The vertical axis is the cumulative distribution function, the proportion of values less than the observed p-value, for the 100 simulated data sets within a condition. A vertical line corresponding to a 0.05 nominal p-value is also provided.