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Table 4 Examples of cancer related genes and proteins regulated by these genes

From: The first step in the development of text mining technology for cancer risk assessment: identifying and organizing scientific evidence in risk assessment literature

Genes

Regulated proteins

p53

Noxa, Puma, p21, Mdm2

PTEN

PIP3, Akt, Cyclin D1

Ras

Raf1, Mek, Erk, Akt

FasL

Caspase-8, Caspase-3, Bid

RB

E2F, Cyclin E, Cyclin A